In Ethiopia the level of maternal mortality and morbidity are among the highest in the world. This is attributed to among other factors, non use of modern health care service by women in Ethiopia. According to the 2005 EDHS, more than seven in ten mothers didn’t receive ANC at all. Therefore, the objective of this study was to examine factors influencing ANC services utilization in Ofa Woreda, Wolaita zone, SNNPR. A community based cross-sectional survey was conducted in Ofa Woreda from January 16- February 3/2011. A multi stage sampling technique was used to select the study population one from urban and the other four from rural. The structured interview questionnaire was administered to the total of 620 study units so as to collect relevant data. Chi-square test and Logistic regression Analyses were done using SPSS. The result of the study revealed that ANC service utilization in the study area was 33%. However, from those who attended ANC service, 58 % started ANC visit during the second & third trimester of pregnancy. Residence, Maternal education, intenseness of pregnancy, women’s occupation, marital status, and household size of women usually live were major socio demographic predictors of ANC service utilization in the area. ANC utilization is far under any acceptable standard in the study area. Among the attendants Significant proportion were not initiated the visit in first trimester. For increasing ANC service utilization; expanding contraceptive choices that enable mothers to find a suitable & more effective method, expanding intensified maternal health care programs particularly in rural areas, awareness raising campaigns and providing education to girls should be emphasize.