Using descriptive research design, total enumeration of college students uncovered factors that support/enhance and hinder their persistence towards degree completion of BS Agriculture and Fisheries (BS Agro-Fisheries) course. The study was conducted using researcher-made questionnaires which determine the student’s demographic characteristics, and the factors that explain their persistence. Persistence factors were measured using perception-survey statements. Results identified the school- and classroom-related factors as support that enhances persistence of BS Agro-Fisheries students. Barriers to achieving their goals were reported as minimal by the students. On the other hand, statement that speaks to “negative” personal/individual experience of the students in the campus calls for another area that needs to be investigated. Results of this study suggested that the program should be prioritized by providing an educational environment with adequate, effective and accessible administrative and educational support services specific for the students’ academic success.